距离基拉和 L 的对峙已经过去了 10 年。死神再次将死亡笔记送往地面,世界因此很快陷入混乱。Tsukuru 是死亡笔记特别工作组的成员,与其他 6 名调查员一起,包括 10 年前经历过基拉案件的松田。美国华尔街、日本涩谷等地发生了因死亡笔记而引发的大屠杀。世界著名的私家侦探龙崎是 L 的合法继承人,他也在调查大屠杀。他们发现世界上存在 6 本死亡笔记。一种名为 Kira 的计算机病毒在世界范围内传播。Kira 病毒中的一条信息要求交出 6 本死亡笔记。拥有 6 本死亡笔记的人将统治世界。希望基拉复活的人与希望阻止它的人之间的对抗开始了。
Jessica and her companions Markus and Mike visit an abandoned factory. But the lost place turns out not to be that lost. Natalia Orlow and her paramilitary army try to hide a bigger secret. And they will keep anybody from leaving the facility alive. The course of events turns out to follow one evil plan of one desperate person. And Jessica herself is the key to its fulfilment. To avert the worst, Jessica needs to fight. For her friend Markus. For her father. And for her life. Until there is only ONE SHOT LEFT.