小雪的母亲和继父在一场车祸中去世，小雪只好带着小雨千里迢迢找到自己的生身父亲李宝康。小雪的继母余丽华不愿接受他们。小雪受了许多委屈，但仍善待每一个人。地产商赵刚公司的司机是导致小雪父母死亡的肇事者，赵刚一直在寻找小雪姐妹。最终，他找到小雪，感动了她，他俩走到了一起。小雪在她生活艰难的阶段干过保姆，拾过破烂，擦过皮鞋，卖过报纸。最终，她的生意越做越大，成为远近闻名的女富豪。小雪不计前嫌，帮助离婚后落魄的继母余丽华与父亲破镜重圆。
一架私人飞机在伦敦郊外的树林中坠毁。机上乘客中有一位前美国大使。托马斯调查了一名成功商人的自杀事件，并发现了与飞机失事的意外联系。
Nikki and the Lyell unit are called in to investigate an ysgou.cc attack against a transgender man.
Thomas and Jack are surprised to see Nikki back at The Lyell, the disappearance of her friend Sally forces her to face her back after her harrowing experience in Mexico.
This year Silent Witness celebrates its 20th anniversary with five explosive stories that take the show into new and uncharted territories as well as delving into the murky depths of city life. Five contemporary thrillers that start amongst the familiar landscapes of London and end up in the dusty scrubland of Mexico.
As Leo's replacement Thomas Chamberlain arrives Nikki investigates the murders of Rachel Freedman, shot in the head, and her little autistic son Nathan, who was poisoned. Nikki rejects policewoman Anne Burchett's theory that Rachel killed them both but is perturbed when an impostor, claiming to be Rachel's sister, visits the morgue. At the same time the disfigured corpse of Eva Liron is discovered, killed with the same poison as Nathan. She had been the nanny to French hot shot footballer Isaac Dreyfus and was planning to blackmail him over a sex tape of them both. Jewish Isaac is a controversial figure due to his anti-Muslim sentiments but he denies ant part in the murders. Then another victim, Isaac's agent Mousa, is discovered dead.
Following a court appearance for drunk driving, Leo is required to perform unpaid work as a punishment, assisting AJ, a community worker on a run-down,largely black-occupied housing estate in South London. AJ is hoping to divert boys away from crime by encouraging them to do sports, and, though initially dismissive of Leo as a white intruder, comes to respect him after he has saved the life of Errol, a former gang member now anxious to keep his little brother Levi out of trouble. Errol has been stabbed in the leg by members of a gang from a rival estate and Leo stops him from bleeding to death. Earlier in the week a young girl called Shana Block was stabbed to death at a funfair and her murder recorded on a mobile phone. As Shana lived on the estate police sergeant Wallace involves Leo as a go-between with the suspicious residents. Also on the scene are Harry and Nikki, the latter dating Ryan, a young Scottish paramedic she met when called to the scene of Shana's death.
The pathologists investigate when a military helicopter crashes into a refugee detention center. Harry and Nikki actually witnessed the crash and were first on the scene but the case is complex since the center was Ministry of Defense property leased to the Home Office. The team is shocked at the conditions they find in the center and Harry, who has a close friend in the RAF, is shaken when a government Minister attributes the accident to pilot error.
When a boat carrying illegal passengers is found crashed in the Thames, the team investigate.
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